Page 90 |
Previous | 93 of 246 | Next |
|
|
small (250x250 max)
medium (500x500 max)
Large
Extra Large
large ( > 500x500)
Full Resolution
|
Loading content ...
44 BUI.LETIX X. C. BOARD OF HEALTH. number of our earlier cases belong- to the very acute or fulminating pellagra, which is an utterly hopeless condition. As we see the disease to-day, we do not consider it so hopeless a proposition. When tho hygienic conditions are bad they should be corrected, but in our experience there are as many cases among the well-conditioned as among the less fortunate. A patient with pellagra should be put at rest, in bed, at least until the diarrhea and stomatitis are relieved. ^riie diet should at first be liquid, preferably milk. Just as in sprue, there is no diet so well suited as milk. Nothing should be added to the milk until the diarrhea is well over, and then one after another of highly nutritious but easily digested articles should be given with caution. It is well at first to avoid fruit and vegetables. Many of these patients are voracious and it is important to hold them in check. Our experience with atoxyl has recently been more encouraging. It should be remembered that this drug is more dangerous than was at first supposed, there being several recorded cases of blindness and death from its too free use. The dose in this country and Great Britain is much smaller than in Germany and Austria. In the former countries it ranges from % of a grain to 3 grains, and in the latter an average of 71/2 grains. In preparing the solution for use no heat should be employed. The.drug should be placed in a sterilized dark bottle and a sufficient quantity of sterile water added to make the desired solution. We u.se the solution in the strength of one to six. On every fourth or fifth day we inject deep into the gluteal muscles TYj grains of atoxyl and carefully watch results. After several injections the dose is gradually decreased. During this treatment the urine should daily be examined for albumen, which, if present, is an indication for the cessation or reduction in the dose of atoxyl. On the intervening days between the doses of atoxyl we have found good results from the use of Sharp & Dohme's arsenite of iron administered in the same way as was the atoxyl. This preparation, while representing only 1-70 grain of arsenic trioxide, seems to have a most beneficial effect. We have in mind one case in particular where the results from this treatment were most gratifying. When the treatment was begun the patient had the well marked, moist lesions on the backs of the hands, an obstinate diarrhea and great weakness. After two weeks the skin lesions and diarrhea were entirely relieved and in six weeks he had gained five pounds in flesh. It should be remembered that pellagra is, in many instances, a self-limiting disease, and oftentimes it is the course of the disease and not the drug that brings about the welcome improvement. There has been recently introduced in Italy a drug called Alma-teina, which is a combination of formaldehyde and hematoxylon and which is supposed to exercise in the intestinal tract the same action as urotropin exercises in the urinary tract. Our experience with it
Object Description
Rating | |
Fixed Title * | NCHH-03: Bulletin of the North Carolina Board of Health [1886-1913] |
Document Title | Bulletin of the North Carolina Board of Health [1886-1913] |
Subject Topical | Public health -- North Carolina -- Periodicals. |
Subject Topical Other | Public Health -- North Carolina -- Periodicals. |
Description | Published: 1886-1913. |
Contributor | North Carolina. State Board of Health. |
Publisher | Wilmington, N.C. : Secretary of the Board, 1886-1913. |
Repository | University of North Carolina at Chapel Hill. Health Sciences Library. |
Host | University of North Carolina at Chapel Hill |
Date | 1909-1910 |
Identifier | NCHH-03-024 |
Form General | Periodicals |
Language | English |
Rights | This item is part of the North Carolina History of Health Digital Collection. Some materials in the Collection are protected by U.S. copyright law. This item is presented by the Health Sciences Library of the University of North Carolina at Chapel Hill for research and educational purposes. It may not be republished or distributed without permission of the Health Sciences Library. |
Digital Collection | North Carolina History of Health Digital Collection |
Sponsor | The North Carolina History of Health Digital Collection is an open access publishing initiative of the Health Sciences Library of the University of North Carolina at Chapel Hill. Financial support for the initiative was provided in part by a multi-year NC ECHO (Exploring Cultural Heritage Online) digitization grant, awarded by the State Library of North Carolina, and funded through the Library Services and Technology Act (LSTA). |
Volume Number | 24 |
Health Discipline | Public Health |
Digital Format | JPEG 2000 |
Print / Download PDF Version | http://archives.hsl.unc.edu/nchh/nchh-03/nchh-03-024.pdf |
Document Sort | all; group-b; nchh-03 |
Volume Link | http://dc.lib.unc.edu/cdm/search/collection/nchh/field/identi/searchterm/NCHH-03-024 |
Title Link | http://dc.lib.unc.edu/cdm/search/collection/nchh/field/documa/searchterm/NCHH-03 |
Catalog Record link | http://search.lib.unc.edu/search?R=UNCb1324480 |
Description
Fixed Title * | Page 90 |
Document Title | Bulletin of the North Carolina Board of Health [1886-1913] |
Subject Topical | Public health -- North Carolina -- Periodicals. |
Subject Topical Other | Public Health -- North Carolina -- Periodicals. |
Description | Published: 1886-1913. |
Contributor | North Carolina. State Board of Health. |
Publisher | Wilmington, N.C. : Secretary of the Board, 1886-1913. |
Repository | University of North Carolina at Chapel Hill. Health Sciences Library. |
Host | University of North Carolina at Chapel Hill |
Date | 1909-1910 |
Identifier | NCHH-03-024-0098 |
Form General | Periodicals |
Page Type | all; article |
Language | English |
Rights | This item is part of the North Carolina History of Health Digital Collection. Some materials in the Collection are protected by U.S. copyright law. This item is presented by the Health Sciences Library of the University of North Carolina at Chapel Hill for research and educational purposes. It may not be republished or distributed without permission of the Health Sciences Library. |
Filename | bulletinofnorthc24nort_0098.jp2 |
Digital Collection | North Carolina History of Health Digital Collection |
Sponsor | The North Carolina History of Health Digital Collection is an open access publishing initiative of the Health Sciences Library of the University of North Carolina at Chapel Hill. Financial support for the initiative was provided in part by a multi-year NC ECHO (Exploring Cultural Heritage Online) digitization grant, awarded by the State Library of North Carolina, and funded through the Library Services and Technology Act (LSTA). |
Volume Number | 24 |
Issue Number | 7 |
Page Number | 90 |
Health Discipline | Public Health |
Full Text | 44 BUI.LETIX X. C. BOARD OF HEALTH. number of our earlier cases belong- to the very acute or fulminating pellagra, which is an utterly hopeless condition. As we see the disease to-day, we do not consider it so hopeless a proposition. When tho hygienic conditions are bad they should be corrected, but in our experience there are as many cases among the well-conditioned as among the less fortunate. A patient with pellagra should be put at rest, in bed, at least until the diarrhea and stomatitis are relieved. ^riie diet should at first be liquid, preferably milk. Just as in sprue, there is no diet so well suited as milk. Nothing should be added to the milk until the diarrhea is well over, and then one after another of highly nutritious but easily digested articles should be given with caution. It is well at first to avoid fruit and vegetables. Many of these patients are voracious and it is important to hold them in check. Our experience with atoxyl has recently been more encouraging. It should be remembered that this drug is more dangerous than was at first supposed, there being several recorded cases of blindness and death from its too free use. The dose in this country and Great Britain is much smaller than in Germany and Austria. In the former countries it ranges from % of a grain to 3 grains, and in the latter an average of 71/2 grains. In preparing the solution for use no heat should be employed. The.drug should be placed in a sterilized dark bottle and a sufficient quantity of sterile water added to make the desired solution. We u.se the solution in the strength of one to six. On every fourth or fifth day we inject deep into the gluteal muscles TYj grains of atoxyl and carefully watch results. After several injections the dose is gradually decreased. During this treatment the urine should daily be examined for albumen, which, if present, is an indication for the cessation or reduction in the dose of atoxyl. On the intervening days between the doses of atoxyl we have found good results from the use of Sharp & Dohme's arsenite of iron administered in the same way as was the atoxyl. This preparation, while representing only 1-70 grain of arsenic trioxide, seems to have a most beneficial effect. We have in mind one case in particular where the results from this treatment were most gratifying. When the treatment was begun the patient had the well marked, moist lesions on the backs of the hands, an obstinate diarrhea and great weakness. After two weeks the skin lesions and diarrhea were entirely relieved and in six weeks he had gained five pounds in flesh. It should be remembered that pellagra is, in many instances, a self-limiting disease, and oftentimes it is the course of the disease and not the drug that brings about the welcome improvement. There has been recently introduced in Italy a drug called Alma-teina, which is a combination of formaldehyde and hematoxylon and which is supposed to exercise in the intestinal tract the same action as urotropin exercises in the urinary tract. Our experience with it |
Digital Format | JPEG 2000 |
Print / Download PDF Version | http://archives.hsl.unc.edu/nchh/nchh-03/nchh-03-024.pdf |
Document Sort | all; group-b; nchh-03 |
Article Title | Pellagra |
Article Author | Wood, Edward J. |
Volume Link | http://dc.lib.unc.edu/cdm/search/collection/nchh/field/identi/searchterm/NCHH-03-024 |
Title Link | http://dc.lib.unc.edu/cdm/search/collection/nchh/field/documa/searchterm/NCHH-03 |
Catalog Record link | http://search.lib.unc.edu/search?R=UNCb1324480 |
Tags
Comments
Post a Comment for Page 90