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II 160 Summary Two hundred and thirteen patients with acute or chronic primary kidney disease or with "hypertensive vascular disease," with or without cardiac involvement, retinopathy or uremia, were treated with a diet limited to rice, sugar, fruit and fruit juices, supplemented by vitamins and iron. The fluid intake was usually limited to 700-1000 cc. of fruit juices daily. The patients followed the diet strictly or with modifications for periods varying from four days to thirty-two months. Protein equilibrium In spite of the low protein intake, the protein equilibrium of the patients on the rice diet is maintained. The nitrogen excretion in the urine decreases to amounts considerably smaller than those found in fasting individuals (the average total nitrogen excretion per twenty-four hours after two months of the diet was 2.26 Gm.). Plasma proteins and hemoglobin remain at a constant level: The average concentration of the total plasma proteins in 120 patients was 6.3 Gm. per 100 cc., both before the rice diet and after ninety days (average) on the diet; the average hemoglobin value of 165 patients was 79.9 per cent (of 15.5 Gm.) before, and 80.1 per cent after seventy-five days (average) on the diet. Plasma and urine chlorides With the low chloride intake of the diet, the chloride concentration in plasma and urine decreases. After a month of the rice diet, the chloride concentration in the urine is about 100 mg. per 1000 cc. The average plasma chloride concentration of 91 non-uremic patients after an average of forty-four days on the rice diet was 91.7 milli-equivalents (as sodium chloride, 536 mg. per 100 cc.), as compared to 97.0 milli-equivalents (as sodium chloride, 567 mg. per 100 cc.) before the diet. Blood pressure Of 192 patients with hypertension on the basis of acute or chronic primary kidney disease or of "hypertensive vascular disease," 25 died after six to eighty-one days on the strict diet (average twenty-five days). In 60 of the remaining 167 patients (36 per cent) there was no improvement in the hypertension: The decrease in their mean arterial pressure was less than 20 mm. of mercury, the average blood pressure decreasing from a level of 196 systolic, 120 diastolic March, 1945 to a level of 180 systolic, 114 diastolic, after an average time of thirty-nine days* on the strict or modified diet. In 10 of 47 patients with chronic primary kidney disease the average blood pressure decreased from a level of 208 systolic, 132 diastolic to a level of 192 systolic, 124 diastolic in an average time of sixty-seven days*. In 22 of 50 patients who had "hypertensive vascular disease" with "secondary" kidney involvement, the average blood pressure decreased from a level of 212 systolic, 129 diastolic to a level of 200 systolic, 126 diastolic after an average of thirty-nine days. In 28 of 65 patients with "hypertensive vascular disease" without conclusive evidence of renal excretory dysfunction, the average blood pressure decreased from a level of 179 systolic, 108 diastolic to a level of 160 systolic, 102 diastolic in an average time of thirty days. In 107 of the 167 patients (61* per cent) the hypertension improved: The decrease in their mean arterial pressure was 20-96.5 mm. of mercury, the average blood pressure decreasing from a level of 200 systolic, 122 diastolic to a level of 149 systolic, 96 diastolic after an average time of sixty-two days on the strict or modified diet. The blood pressure of 5 patients with acute glomerulonephritis decreased from a level of 170 systolic, 109 diastolic (average) to 108 systolic, 66 diastolic (average), in an average period of fifteen days on the rice diet. In 37 of 47 patients with chronic primary kidney disease, the average blood pressure decreased from a level of 194 systolic, 124 diastolic to a level of 140 systolic, 96 diastolic after seventy-seven days (average) on the rice diet. In 28 of 50 patients with "hypertensive vascular disease" with "secondary" kidney involvement, the average blood pressure decreased from a level of 219 systolic, 128 diastolic to a level of 165 systolic, 102 diastolic in an average of seventy-three days. In 37 of 65 patients with "hypertensive vascular disease" without conclusive evidence of renal excretory dysfunction, the average blood pressure decreased from a level of 197 systolic, 115 diastolic to a level of 151 systolic, 97 diastolic after an average of forty-eight days on the rice diet. Electrocardiographic changes In 23 of 82 patients with chronic primary kidney disease or "hypertensive vascular * The average figure may be misleading because it includes one patient who was on the diet for 548 days. NORTH CAROLINA MEDICAL JOURNAL
Object Description
Rating | |
Fixed Title * | NCHH-17: North Carolina Medical Journal [1940-2001] |
Document Title | North Carolina Medical Journal [1940-2001] |
Subject Topical Other | Public Health -- Periodicals.; Physicians -- North Carolina -- Directory.; Societies, Medical -- North Carolina -- Periodicals. |
Description | Includes Transactions of the Society, -1960; 1961- , Transactions issued separately, bound in.; Includes Transactions of the auxiliary to the Medical Society of the State of North Carolina and Proceedings of the North Carolina Public Health Association. Official organ of the Medical Society of the State of North Carolina, 1940-May 1972; of the North Carolina Medical Society, June 1972-. Vols. for 1940-May 1972 published by the Medical Society of the State of North Carolina; June 1972- by the North Carolina Medical Society. |
Contributor | Medical Society of the State of North Carolina. Transactions.; Medical Society of the State of North Carolina.; North Carolina Medical Society.; North Carolina Medical Society. Transactions.; North Carolina Public Health Association. Proceedings. |
Publisher | [Winston-Salem] : North Carolina Medical Society [etc.], 1940- |
Repository | University of North Carolina at Chapel Hill. Health Sciences Library. |
Host | University of North Carolina at Chapel Hill |
Date | 1945 |
Identifier | NCHH-17-006 |
Form General | Periodicals |
Language | English |
Rights | This item is part of the North Carolina History of Health Digital Collection. Some materials in the Collection are protected by U.S. copyright law. This item is presented by the Health Sciences Library of the University of North Carolina at Chapel Hill for research and educational purposes. It may not be republished or distributed without permission of the Health Sciences Library. |
Digital Collection | North Carolina History of Health Digital Collection |
Sponsor | The North Carolina History of Health Digital Collection is an open access publishing initiative of the Health Sciences Library of the University of North Carolina at Chapel Hill. Financial support for the initiative was provided in part by a multi-year NC ECHO (Exploring Cultural Heritage Online) digitization grant, awarded by the State Library of North Carolina, and funded through the Library Services and Technology Act (LSTA). |
Volume Number | 6 |
Health Discipline | Medicine |
Digital Format | JPEG 2000 |
Print / Download PDF Version | http://archives.hsl.unc.edu/nchh/nchh-17/nchh-17-006.pdf |
Document Sort | all; nchh-17 |
Volume Link | http://dc.lib.unc.edu/cdm/search/collection/nchh/field/identi/searchterm/NCHH-17-006 |
Title Link | http://dc.lib.unc.edu/cdm/search/collection/nchh/field/documa/searchterm/NCHH-17 |
Catalog Record link | http://search.lib.unc.edu/search?R=UNCb1306322 |
Description
Fixed Title * | Page 160 |
Document Title | North Carolina Medical Journal [1940-2001] |
Subject Topical Other | Public Health -- Periodicals.; Physicians -- North Carolina -- Directory.; Societies, Medical -- North Carolina -- Periodicals. |
Description | Includes Transactions of the Society, -1960; 1961- , Transactions issued separately, bound in.; Includes Transactions of the auxiliary to the Medical Society of the State of North Carolina and Proceedings of the North Carolina Public Health Association. Official organ of the Medical Society of the State of North Carolina, 1940-May 1972; of the North Carolina Medical Society, June 1972-. Vols. for 1940-May 1972 published by the Medical Society of the State of North Carolina; June 1972- by the North Carolina Medical Society. |
Contributor | Medical Society of the State of North Carolina. Transactions.; Medical Society of the State of North Carolina.; North Carolina Medical Society.; North Carolina Medical Society. Transactions.; North Carolina Public Health Association. Proceedings. |
Publisher | [Winston-Salem] : North Carolina Medical Society [etc.], 1940- |
Repository | University of North Carolina at Chapel Hill. Health Sciences Library. |
Host | University of North Carolina at Chapel Hill |
Date | 1945 |
Identifier | NCHH-17-006-0172 |
Form General | Periodicals |
Page Type | all; article |
Language | English |
Rights | This item is part of the North Carolina History of Health Digital Collection. Some materials in the Collection are protected by U.S. copyright law. This item is presented by the Health Sciences Library of the University of North Carolina at Chapel Hill for research and educational purposes. It may not be republished or distributed without permission of the Health Sciences Library. |
Filename | northcarolinamed61945medi_0172.jp2 |
Digital Collection | North Carolina History of Health Digital Collection |
Sponsor | The North Carolina History of Health Digital Collection is an open access publishing initiative of the Health Sciences Library of the University of North Carolina at Chapel Hill. Financial support for the initiative was provided in part by a multi-year NC ECHO (Exploring Cultural Heritage Online) digitization grant, awarded by the State Library of North Carolina, and funded through the Library Services and Technology Act (LSTA). |
Volume Number | 6 |
Issue Number | 3 |
Page Number | 160 |
Health Discipline | Medicine |
Full Text | II 160 Summary Two hundred and thirteen patients with acute or chronic primary kidney disease or with "hypertensive vascular disease" with or without cardiac involvement, retinopathy or uremia, were treated with a diet limited to rice, sugar, fruit and fruit juices, supplemented by vitamins and iron. The fluid intake was usually limited to 700-1000 cc. of fruit juices daily. The patients followed the diet strictly or with modifications for periods varying from four days to thirty-two months. Protein equilibrium In spite of the low protein intake, the protein equilibrium of the patients on the rice diet is maintained. The nitrogen excretion in the urine decreases to amounts considerably smaller than those found in fasting individuals (the average total nitrogen excretion per twenty-four hours after two months of the diet was 2.26 Gm.). Plasma proteins and hemoglobin remain at a constant level: The average concentration of the total plasma proteins in 120 patients was 6.3 Gm. per 100 cc., both before the rice diet and after ninety days (average) on the diet; the average hemoglobin value of 165 patients was 79.9 per cent (of 15.5 Gm.) before, and 80.1 per cent after seventy-five days (average) on the diet. Plasma and urine chlorides With the low chloride intake of the diet, the chloride concentration in plasma and urine decreases. After a month of the rice diet, the chloride concentration in the urine is about 100 mg. per 1000 cc. The average plasma chloride concentration of 91 non-uremic patients after an average of forty-four days on the rice diet was 91.7 milli-equivalents (as sodium chloride, 536 mg. per 100 cc.), as compared to 97.0 milli-equivalents (as sodium chloride, 567 mg. per 100 cc.) before the diet. Blood pressure Of 192 patients with hypertension on the basis of acute or chronic primary kidney disease or of "hypertensive vascular disease" 25 died after six to eighty-one days on the strict diet (average twenty-five days). In 60 of the remaining 167 patients (36 per cent) there was no improvement in the hypertension: The decrease in their mean arterial pressure was less than 20 mm. of mercury, the average blood pressure decreasing from a level of 196 systolic, 120 diastolic March, 1945 to a level of 180 systolic, 114 diastolic, after an average time of thirty-nine days* on the strict or modified diet. In 10 of 47 patients with chronic primary kidney disease the average blood pressure decreased from a level of 208 systolic, 132 diastolic to a level of 192 systolic, 124 diastolic in an average time of sixty-seven days*. In 22 of 50 patients who had "hypertensive vascular disease" with "secondary" kidney involvement, the average blood pressure decreased from a level of 212 systolic, 129 diastolic to a level of 200 systolic, 126 diastolic after an average of thirty-nine days. In 28 of 65 patients with "hypertensive vascular disease" without conclusive evidence of renal excretory dysfunction, the average blood pressure decreased from a level of 179 systolic, 108 diastolic to a level of 160 systolic, 102 diastolic in an average time of thirty days. In 107 of the 167 patients (61* per cent) the hypertension improved: The decrease in their mean arterial pressure was 20-96.5 mm. of mercury, the average blood pressure decreasing from a level of 200 systolic, 122 diastolic to a level of 149 systolic, 96 diastolic after an average time of sixty-two days on the strict or modified diet. The blood pressure of 5 patients with acute glomerulonephritis decreased from a level of 170 systolic, 109 diastolic (average) to 108 systolic, 66 diastolic (average), in an average period of fifteen days on the rice diet. In 37 of 47 patients with chronic primary kidney disease, the average blood pressure decreased from a level of 194 systolic, 124 diastolic to a level of 140 systolic, 96 diastolic after seventy-seven days (average) on the rice diet. In 28 of 50 patients with "hypertensive vascular disease" with "secondary" kidney involvement, the average blood pressure decreased from a level of 219 systolic, 128 diastolic to a level of 165 systolic, 102 diastolic in an average of seventy-three days. In 37 of 65 patients with "hypertensive vascular disease" without conclusive evidence of renal excretory dysfunction, the average blood pressure decreased from a level of 197 systolic, 115 diastolic to a level of 151 systolic, 97 diastolic after an average of forty-eight days on the rice diet. Electrocardiographic changes In 23 of 82 patients with chronic primary kidney disease or "hypertensive vascular * The average figure may be misleading because it includes one patient who was on the diet for 548 days. NORTH CAROLINA MEDICAL JOURNAL |
Digital Format | JPEG 2000 |
Print / Download PDF Version | http://archives.hsl.unc.edu/nchh/nchh-17/nchh-17-006.pdf |
Document Sort | all; nchh-17 |
Article Title | Compensation Of Renal Metabolic Dysfunction Treatment Of Kidney Disease And Hypertensive Vascular Disease Ivith Rice Diet, Iii |
Article Author | Walter Kempner |
Volume Link | http://dc.lib.unc.edu/cdm/search/collection/nchh/field/identi/searchterm/NCHH-17-006 |
Title Link | http://dc.lib.unc.edu/cdm/search/collection/nchh/field/documa/searchterm/NCHH-17 |
Catalog Record link | http://search.lib.unc.edu/search?R=UNCb1306322 |
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